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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: Rationale for Combining the BCL2 Inhibitor Venetoclax with the PI3K Inhibitor Bimiralisib in the Treatment of IDH2- and FLT3-Mutated Acute Myeloid Leukemia
doi: 10.3390/ijms232012587
Figure Lengend Snippet: Characteristics of leukemia and lymphoma cell lines.
Article Snippet: Human AML cells lines OCI-AML3 (AML-M4, FLT3wt, DNMT3A R882C, NPM1mut, and TP53wt), MOLM-13 (AML-M5, t(9;11), FLT3-ITD, and TP53wt), MOLM-16 (AML-M0, FLT3wt, TP53mut), ML-2 (AML-M4, t(6;11), FLT3wt, TP53mut) and HL-60 (AML-M2, FLT3wt, and TP53 null) as well as
Techniques:
Journal: International Journal of Molecular Sciences
Article Title: Rationale for Combining the BCL2 Inhibitor Venetoclax with the PI3K Inhibitor Bimiralisib in the Treatment of IDH2- and FLT3-Mutated Acute Myeloid Leukemia
doi: 10.3390/ijms232012587
Figure Lengend Snippet: IC50 values cell lines (μM).
Article Snippet: Human AML cells lines OCI-AML3 (AML-M4, FLT3wt, DNMT3A R882C, NPM1mut, and TP53wt), MOLM-13 (AML-M5, t(9;11), FLT3-ITD, and TP53wt), MOLM-16 (AML-M0, FLT3wt, TP53mut), ML-2 (AML-M4, t(6;11), FLT3wt, TP53mut) and HL-60 (AML-M2, FLT3wt, and TP53 null) as well as
Techniques:
Journal: International Journal of Molecular Sciences
Article Title: Rationale for Combining the BCL2 Inhibitor Venetoclax with the PI3K Inhibitor Bimiralisib in the Treatment of IDH2- and FLT3-Mutated Acute Myeloid Leukemia
doi: 10.3390/ijms232012587
Figure Lengend Snippet: Combination index values of AML cell lines.
Article Snippet: Human AML cells lines OCI-AML3 (AML-M4, FLT3wt, DNMT3A R882C, NPM1mut, and TP53wt), MOLM-13 (AML-M5, t(9;11), FLT3-ITD, and TP53wt), MOLM-16 (AML-M0, FLT3wt, TP53mut), ML-2 (AML-M4, t(6;11), FLT3wt, TP53mut) and HL-60 (AML-M2, FLT3wt, and TP53 null) as well as
Techniques: